Apaf1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comApaf1 ELISA Kit for Rat(Rattus norvegicus)

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Apaf1 (Gene name),

Apoptotic protease-activating factor 1 (Protein name ), APAF_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Apaf1;

Protein name:

Apoptotic protease-activating factor 1(APAF-1);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Monomer. Oligomerizes upon binding of cytochrome c and dATP. Oligomeric Apaf-1 and pro-caspase-9 bind to each other via their respective NH2-terminal CARD domains. Interacts with UACA. Interacts with APIP.

Function:

Regulates progammed cell death; necessary for normal brain development. Participates with caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

1249

Sequence:

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1150:

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1249:

KWWNVVTGES | SQTFYTNGTN | LKKIHVSPDF | RTYVTVDNLG | ILYILQVLE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.64522

SMR:

Q9EPV5

KEGG:

rno:78963

Pfam:

PF00619

STRING:

10116.ENSRNOP00000010869

String:

Q9EPV5

Uniprot:

Q9EPV5

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ELISA Kit for Rat APAF-1

Cat.:

E1054m

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Packing:

96T

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ELISA Kit for Rat APAF-1

Cat.:

E1054r

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96T

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ELISA Kit for Rat APAF-1

Cat.:

E1054h

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MSDS:

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Packing:

96T

ELISA Kit for Rat APAF-1

Cat.:

E1054d

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MSDS:

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Packing:

96T

CLIA Kit for Rat APAF-1

Cat.:

U1054m

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MSDS:

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Packing:

96T

CLIA Kit for Rat APAF-1

Cat.:

U1054h

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MSDS:

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Packing:

96T

CLIA Kit for Rat APAF-1

Cat.:

U1054r

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rat APAF-1

Cat.:

U1054d

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Packing:

96T

Polyclonal Antibody for Rat APAF-1

Cat.:

P1054Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat APAF-1

Cat.:

P1054Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat APAF-1

Cat.:

P1054Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat APAF-1

Protein for Rat APAF-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

Itoh T. , Itoh A. , Pleasure D.
Submitted (2000-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
2.

"Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury."
Yakovlev A.G. , Ota K. , Wang G. , Movsesyan V. , Bao W.-L. , Yoshihara K. , Faden A.I.
J. Neurosci.21:7439-7446(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE;INDUCTION BY BRAIN INJURY

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